HPUS Timeline and Statistics

Copy of Untitled Design (3)

From its earliest roots in 19th century pharmacopeias to its modern digital format, the Homoeopathic Pharmacopeia of the United States (HPUS) has evolved alongside the regulatory landscape. This newly added timeline illustrates key milestones in the development, publication, and legal recognition of the HPUS — offering a clear view of how homeopathic standards have taken shape over time.

Continue scrolling beyond the timeline to view a history of monographs that have been completed and approved over time.

1841
Jahr's Pharmacopoeia and Posology, which appeared in Germany, was translated into English by Kitchen and published in Philadelphia in 1850

1868
American Institute of Homeopathy's (AIH) Committee to Produce a Dispensatory makes first attempt at a U.S. publication

1882
First independent U.S. publication: Boericke & Tafel publish the American Homoeopathic Pharmacopoeia

1890s
American Institute of Homeopathy reconvenes in earnest the
Committee on Pharmacy which publishes a useable reference volume in 1897

1897
Committee on Pharmacy of the American Institute of Homeopathy; Pharmacopeia of the American Institute of Homeopathy (Otis Clapp, Boston), First Edition

1901
Second edition published, renamed Homoeopathic Pharmacopoeia of the United States (Mohr/Clapp)

1906
Passage of the Pure Food and Drug Act

1914
Third Edition published (T.H. Carmichael/Clapp)

1936
Fourth Edition published (T.H. Carmichael)

1938
Passage of the Food, Drug, and Cosmetic Act

Fifth Edition published (T.H. Carmichael)

1941
Sixth Edition published (T.H. Carmichael)

1962
Passage of the Kefauver-Harris Amendment

1964
Seventh Edition published (Roger Schmidt)

1974
Compendium of Hometherapeutics
(Baker)

1978
Eighth Edition: Volume One published (Rogers/Baker)

1980
HPCUS is incorporated as an independent body

1982
Eighth Edition: Supplement A published (Baker)

1983-1987
Development of Compliance Policy Guide 7132.15

1988
HPUS Revision Service (HPRS)

1990
Compliance Policy Guide 7132.15 becomes effective

HPRS is complete with semi-annual updates; supersedes Compendium and Supplement A as the official compendium

1992-2003
Monographs, general pharmacy, and standards & controls receive semi-annual updates

2004
HPUS begins online with immediate, real-time updates

2022
FDA withdraws Compliance Policy Guide 7132.15 and publishes Enforcement Guidance

Monographs by the Numbers

=    1,311 current monographs