HPUS Timeline and Statistics
From its earliest roots in 19th century pharmacopeias to its modern digital format, the Homoeopathic Pharmacopeia of the United States (HPUS) has evolved alongside the regulatory landscape. This newly added timeline illustrates key milestones in the development, publication, and legal recognition of the HPUS — offering a clear view of how homeopathic standards have taken shape over time.
Continue scrolling beyond the timeline to view a history of monographs that have been completed and approved over time.
1841
Jahr's Pharmacopoeia and Posology, which appeared in Germany, was translated into English by Kitchen and published in Philadelphia in 1850
1868
American Institute of Homeopathy's (AIH) Committee to Produce a Dispensatory makes first attempt at a U.S. publication
1882
First independent U.S. publication: Boericke & Tafel publish the American Homoeopathic Pharmacopoeia
1890s
American Institute of Homeopathy reconvenes in earnest the
Committee on Pharmacy which publishes a useable reference volume in 1897
1897
Committee on Pharmacy of the American Institute of Homeopathy; Pharmacopeia of the American Institute of Homeopathy (Otis Clapp, Boston), First Edition
1901
Second edition published, renamed Homoeopathic Pharmacopoeia of the United States (Mohr/Clapp)
1906
Passage of the Pure Food and Drug Act
1914
Third Edition published (T.H. Carmichael/Clapp)
1936
Fourth Edition published (T.H. Carmichael)
1938
Passage of the Food, Drug, and Cosmetic Act
Fifth Edition published (T.H. Carmichael)
1941
Sixth Edition published (T.H. Carmichael)
1962
Passage of the Kefauver-Harris Amendment
1964
Seventh Edition published (Roger Schmidt)
1974
Compendium of Hometherapeutics (Baker)
1978
Eighth Edition: Volume One published (Rogers/Baker)
1980
HPCUS is incorporated as an independent body
1982
Eighth Edition: Supplement A published (Baker)
1983-1987
Development of Compliance Policy Guide 7132.15
1988
HPUS Revision Service (HPRS)
1990
Compliance Policy Guide 7132.15 becomes effective
HPRS is complete with semi-annual updates; supersedes Compendium and Supplement A as the official compendium
1992-2003
Monographs, general pharmacy, and standards & controls receive semi-annual updates
2004
HPUS begins online with immediate, real-time updates
2022
FDA withdraws Compliance Policy Guide 7132.15 and publishes Enforcement Guidance
